Sonata & Serenade are organic-use approved biologicals (bacterias) that are effective in controlling powdery and downy mildews. The actual label can be viewed at the following : http://www.agraquest.com/agrochemical/products/fungicides-sonata.php
-low toxicity - 0-day re-entry period to fields
-can be applied through drip irrigation
-can be used throughout the growing season, 7-14 day effectiveness
-compatible with fertilizers and most fungicides
- cost effective
The active ingredient is a dormant bacteria which inocculates the field upon appllication. The spray is most effective if it is sprayed when spray droplet evaporation rates are low. Early morning or evening sprays are suggested. The longer the moisture remains; the better the inocculation. Some growers "jump-start" the bacteria by tank mixing with molasses and fish emulsion fertilizer (bacteria tea). Addition of a rainfast spreader-sticker improves performance. Recommended to alternate between Serenade & Sonata for broad-spectrum control.
These biologicals take time to activate and are best applied prior to disease-favorable conditions occurring. Applications of additional fungicides typically don't affect their performance; as they are bacterias, not fungii.
I use these in our hop propagation process where environmental conditions (warm & humid, wet-leaf conditions) can be optimum for hop diseases like downy and powdery mildews; as well as botrytis, anthracnose, pythium, & sclerotinia to develop. These products are quite effective in controlling disease infection on emerging shoots as well as stopping the infection of new growth. Incidence of other diseases like Botrytis and Pythium are notably reduced.